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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCC1
All Species:
20.61
Human Site:
S387
Identified Species:
37.78
UniProt:
P18754
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P18754
NP_001041659.1
421
44969
S387
G
Q
D
E
D
A
W
S
P
V
E
M
M
G
K
Chimpanzee
Pan troglodytes
XP_001152659
421
44920
S387
G
Q
D
E
D
A
W
S
P
V
E
M
T
G
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544458
630
67681
S596
G
Q
E
D
D
A
W
S
P
V
E
M
T
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8VE37
421
44912
S387
G
Q
D
E
D
A
W
S
P
V
E
M
T
G
K
Rat
Rattus norvegicus
NP_001121661
421
45093
S387
G
Q
E
D
D
A
W
S
P
V
E
M
T
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_427366
194
21051
M162
P
V
R
G
K
G
K
M
R
F
Q
D
A
F
C
Frog
Xenopus laevis
P25183
424
45052
S392
G
E
E
E
D
V
W
S
P
E
Q
M
T
G
K
Zebra Danio
Brachydanio rerio
Q6NYE2
495
54133
E450
K
S
S
T
T
A
Q
E
V
K
T
L
D
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25171
547
58832
L386
V
G
D
G
D
D
E
L
E
P
I
V
V
V
S
Honey Bee
Apis mellifera
XP_394158
439
46956
E400
G
E
E
E
D
V
E
E
P
T
L
V
K
G
K
Nematode Worm
Caenorhab. elegans
Q18211
569
61466
W516
E
D
G
T
A
Y
A
W
G
F
D
T
T
G
Q
Sea Urchin
Strong. purpuratus
XP_001191815
424
45249
H392
G
D
E
D
E
D
L
H
V
P
T
K
I
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P21827
482
52995
E436
G
P
F
E
D
D
T
E
V
P
T
R
I
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
N.A.
64.7
N.A.
93.8
93.3
N.A.
N.A.
37
75.9
22.2
N.A.
29
45.5
29.5
52.8
Protein Similarity:
100
99.7
N.A.
65.8
N.A.
96.9
96.6
N.A.
N.A.
42
85.6
40
N.A.
43.6
63
42.5
70.7
P-Site Identity:
100
93.3
N.A.
80
N.A.
93.3
80
N.A.
N.A.
0
60
13.3
N.A.
13.3
40
6.6
6.6
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
80
20
N.A.
26.6
60
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
47
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
16
31
24
70
24
0
0
0
0
8
8
8
0
0
% D
% Glu:
8
16
39
47
8
0
16
24
8
8
39
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
16
0
0
0
8
0
% F
% Gly:
70
8
8
16
0
8
0
0
8
0
0
0
0
70
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
8
0
16
8
0
% I
% Lys:
8
0
0
0
8
0
8
0
0
8
0
8
8
8
54
% K
% Leu:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
47
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% N
% Pro:
8
8
0
0
0
0
0
0
54
24
0
0
0
0
0
% P
% Gln:
0
39
0
0
0
0
8
0
0
0
16
0
0
0
8
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
47
0
0
0
0
0
0
16
% S
% Thr:
0
0
0
16
8
0
8
0
0
8
24
8
47
0
0
% T
% Val:
8
8
0
0
0
16
0
0
24
39
0
16
8
8
8
% V
% Trp:
0
0
0
0
0
0
47
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _